Ocular Surface Disease: Medical and Surgical Management by Mark J. Mannis, Edward J. Holland

By Mark J. Mannis, Edward J. Holland

Ocular floor sickness: clinical and Surgical administration is the one accomplished and definitive textual content at the scientific and surgical administration of the ailments of the ocular floor. The editors are world-renowned corneal experts who've recruited leaders within the box of ocular floor ailment to give a contribution chapters. transparent diagnostic and healing classifications and surgical innovations are included. For the working towards ophthalmologist, either corneal expert and common ophthalmologist, this can be the authoritative textual content at the clinical and surgical administration of ocular floor issues.

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This requires a de- 25 2. Classification of Ocular Surface Disease fined quality and quantity of the three major components of the tear film, that is, the lipid phase, the aqueous phase, and the mucin phase. A poorly lubricated ocular surface is vulnerable to minute environmental challenges and can undergo various pathological changes. 77,78 In addition, tears need to be distributed on the ocular surface, a process that requires normal lid configuration. Alterations of each of the components of the ocular surface cause disturbances of the entire tear film system that can lead to pathological changes of the surface epithelia.

Primary acquired lacrimal disease is the most common form of dry eye and has been seen as a primary, agerelated condition. However, many patients show inflammatory changes of the conjunctiva that are similar to those in Sjögren’s syndrome. 116 However, it is currently unclear whether androgens can also modulate conjunctival inflammation in the context of aqueous tear deficiency. Other causes of primary lacrimal gland disease are rare cases of congenital absence of the main lacrimal gland, as well as familial dysautonomia (Riley–Day syndrome).

However, many patients show inflammatory changes of the conjunctiva that are similar to those in Sjögren’s syndrome. 116 However, it is currently unclear whether androgens can also modulate conjunctival inflammation in the context of aqueous tear deficiency. Other causes of primary lacrimal gland disease are rare cases of congenital absence of the main lacrimal gland, as well as familial dysautonomia (Riley–Day syndrome). , in the context of sarcoidosis or AIDS. Similarly, graft-versus-host disease and irradiation can cause dysfunction of the lacrimal glands.

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