Cation Flux Across Biomembranes by Yasuo Mukohata

By Yasuo Mukohata

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139:715. , Witonsky, R. J. , Trachtman, M. , and Lentz, B. (1970). Biochem. Biophys. Acta 223:1. C. (1963). Trans. Farady S o c , 59:1126. , and De Weer, P. (1976). Arch. Biochem. Biophys. 173:386. , and Katabami, H. (1978). This symposium. , and Yoshida, H. (1966). J. Biochem. 59:295. E. (197U). J. Biol. Chem. 2^9:1+911. L. Hegyvary, C , and Kume, S. (1972). J. Biol. Chem. 2^7:6530. , and Kume, S. (1973). J. Biol. Chem. 2U8:6993. N. (1973). , eds). p 203. Academic Press, New York and London. N.

231-278. University Park Press, Baltimore. L. (1978). J. Biol. Chem. 253:6853-6862. , and Tonomura, Y. (1975). J. Biochem. 77:533-541. P. (1976). Current Topics in Membranes and Transport 8:29-97. D. (1975). Annu. Rev. Physiol. 37:13-55. , and Schwartz, W. (1978). J. Gen. Physiol. 72:409-442. L. (1975a). Q. Rev. Biophys. 7:239-274. W. (1978). Biochim. Biophys. Acta 527:115-130. M. (1978a) Biochim. Biophys. Acta 525:230-251. M. (1978b) Biochim. Biophys. Acta 525:252-264. J. (1972) In "Role of Membranes in Secretory Processes" (L.

Lacaz-Vieiraefa/. l Effect of ouabain on the short-circuit current (SCC) and on the rate of 42-K discharge into the outer bathing regarding j£-,. solution, J ^ . Insert: computer predictions See text for details. in agreement with the experimental results. Simulation of Na pump inhibition predicts transient increase in J^ , followed by a decline with time (see insert, curve b ) . l) except for the final steady state value which did not fall below the control steady-state value. Reasons for this discrepancy are unknown.

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