Atlas of the Prostate by John D. McConnell (auth.), Reginald C. Bruskewitz MD (eds.)

By John D. McConnell (auth.), Reginald C. Bruskewitz MD (eds.)

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N Engl J Med 1992,327:1234-1236. 45. Stoner E: Three year safety and efficacy data on the use of finasteride in the treatment of benign prostatic hyperplasia. The Finasteride Study Group. Urology 1994,43:284-292. 71. Kirby RS: Doxazosin in benign prostatic hyperplasia: effects on blood rressure and urinary flow in normotensive and hypertensive men. Urology 1995, 46:182-186. 46. : Biologic variability of prostate-specific antigen and its usefulness as a marker for prostate cancer: effects of finasteride.

Long-term use of medical therapies for benign prostatic hyperplasia. This figure summarizes the efficacy and safety data for medical therapies over longer periods. Patients were recruited de novo into the 5a-reductase study while the a-blocker studies followed patients who had previously been in other trials using the same drug. As noted in Effect Overall Dropout Rate, % 43 -Blockers Prazo in, % Phenoxybenzamine, % Terazo in, % Do azo in, % Tam ufo in, % 10-15 15- 17 1 -1 NI 10 NI NI 15-20 10-14 15 5-8 10-1 I 8 2- 8 7- 14 +-10 2- 7 110- 15 - 10 1 1- 2 <1 I <1 15 19 8 8 <1 1 4-8 <1 _ FIGURE 3-23.

69. : Doxazosin in the treatment of benign prostatic hyperplasia in normotensive patients: a multicenter study. J Uro/1995, 154:129-130. 43. : Effect of finasteride on serum PSA concentration in men with benign prostatic hyperplasia: results from the North American phase II clinical trial. Urol Clin North Am 1993, 20:627-636. 70. : Doxazosin for the tre

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