An Illustrated Pocketbook of Parkinson’s Disease and Related by G. David Perkin

By G. David Perkin

An authoritative creation to Parkinson's ailment and its similar problems and syndromes, this ebook presents a concise assessment of the sickness and its analysis and administration. the writer provides samples of scientific, investigative (CT, MRI, and PET), and pathological photographs with succinct descriptive textual content of the problems featured. He describes the stipulations relating to Parkinson's disorder, and the photographs offer pathological macroscopic and microscopic sections, a variety of imaging stories, and information of circulate problems in most cases. The publication will function an invaluable instructing software that demonstrates the imaging and pathology of the illness.

Show description

Read or Download An Illustrated Pocketbook of Parkinson’s Disease and Related Disorders PDF

Best neuroscience books

Biopsychology (4th Edition)

Written in a pleasant and fascinating demeanour, Pinel's Biopsychology introduces the basics of recent biopsychology. The fourth variation has been completely up-to-date to maintain Biopsychology abreast of the numerous contemporary advancements during this speedily altering box. regardless of the numerous infusion of recent fabric, Pinel's textual content keeps the culture that has made it so successful: transparent, attractive prose; an unwavering emphasis on habit; an enticing, fantastically designed and built-in representation package deal; and insight-provoking money owed of recent biopsychological study.

Placebo and Pain: From Bench to Bedside

The placebo influence keeps to fascinate scientists, students, and clinicians, leading to a powerful volume of study, quite often within the box of discomfort. whereas contemporary experimental and scientific experiences have unraveled salient facets of the neurobiological substrates and medical relevance of discomfort and placebo analgesia, an authoritative resource remained missing beforehand.

Physical Control of the Mind: Toward a Psychocivilized Society

Actual regulate of the brain through direct manipulation of the mind is a singular occasion in human historical past. during this quantity, Dr. Jose M. R. Delgado describes his pioneering paintings in implanting electrodes within the brains of cats, monkeys, and males. via electric stimulation of particular cerebral buildings, Delgado demonstrates how events should be prompted by means of radio command, hostility might seem or disappear, social hierarchy will be transformed, sexual habit will be replaced, and reminiscence, feelings, and the considering technique can be inspired through handheld remote control.

Extra resources for An Illustrated Pocketbook of Parkinson’s Disease and Related Disorders

Sample text

Drug-induced movements in these patients usually take the form of dystonia rather than chorea. Certain other clinical features are suggestive of the disease and are notoriously difficult to manage. These include postural instability with falls, excessive snoring associated with vocal cord abductor palsy, and anterocollis. Management of the postural hypotension includes the use of elastic Table 3 Multiple system atrophy: proposed clinical diagnostic criteria Definite Probable PLUS Severe symptomatic autonomic failure Striatonigral type (predominantly parkinsonism) Olivopontocerebellar type (predominantly cerebellar) Postmortem confirmation Sporadic adult-onset Non—or poorly levadopa-responsive Postmortem confirmation Sporadic adult-onset Cerebellar syndrome (with or without parkinsonism or pyramidal signs) 32 AN ILLUSTRATED POCKETBOOK OF PARKINSON’S DISEASE Figure 32 Striatonigral degeneration: histology of putamen Striatonigral type (predominantly parkinsonism) OR Cerebellar signs OR Pyramidal signs OR Olivopontocerebellar type (predominantly cerebellar) PLUS Severe symptomatic autonomic failure OR Pathological sphincter electromyogram pathological sphincter electromyogram Possible Sporadic, adult-onset, non- or poorly Sporadic adult-onset cerebellar levadopa-responsive parkinsonism syndrome with parkinsonism Adult onset, 30 years of age; sporadic, no multiple system atrophy in first—or second-degree relatives; autonomic failure, postural syncope and/or urinary incontinence or retention due to other causes; levadopa-responsive, moderate or good levadopa response accepted if waning and multiple atypical features present; parkinsonism, no dementia, areflexia, or supranuclear down-gaze palsy stockings, raising the head of the bed by 10°, fludrocortisone or a sympathomimetic agent.

Segmental myoclonus originates from a brain stem or spinal level. The movements are more or less continuous, usually at around 1–3 Hz, and explicable by discharges from contiguous anatomical levels (Figure 70). Palatal myoclonus is a rhythmic contraction of the soft palate, frequently accompanied by contraction of other muscles of the pharynx and larynx, sometimes to the face and even the diaphragm. Typically, it follows pontine infarction, often after a latent period of several weeks or months.

PET using [18F] fluorodeoxyglucose has been used to measure local cerebral metabolic rates for glucose in both multiple system atrophy and in sporadic and familial forms of OPCA. In the former two, reduced metabolic activity, albeit to differing degrees, is found in the brain stem, cerebellum, putamen, thalamus, and cerebral cortex. In familial OPCA, changes are confined to the brain stem and cerebellum (Figure 41). AN ILLUSTRATED POCKETBOOK OF PARKINSON’S DISEASE 35 Figure 37 Histology of multiple system atrophy with olivopontocerebellar atrophy (OPCA).

Download PDF sample

Rated 4.77 of 5 – based on 39 votes