Aging and Recovery of Function in the Central Nervous System by Stanley Finger, David Wozniak (auth.), Stephen W. Scheff

By Stanley Finger, David Wozniak (auth.), Stephen W. Scheff (eds.)

The mammalian important frightened procedure is a striking constitution which has attracted many new investigators, as evidenced via the dramatic raise in clinical guides facing neurobiology. on a daily basis uncomplicated scientists behavior new and intriguing experiments, leading to outstanding discoveries des­ tined to aid mankind. regrettably lots of those new findings are gradual to be authorized via the scientific international. this can be very true within the sector of mind trauma, the place the current diagnosis is mostly very negative. we've recognized for relatively it slow that the mammalian vital anxious approach is able to compensating for serious harm in lots of alternative ways, and less than a few conditions behav­ ioral repayment could be saw. although, a lot continues to be to be discovered concerning the different factors and occasions that bring about practical restoration and people condi­ tions that don't. it truly is this problem that initially excited some of the individuals to this quantity to discover the topic of restoration from mind harm. One consider specific that's recognized to alter the diagnosis of restoration is the age of the organism on the time of the wear. This publication is an try to discover this crucial variable. lots of the literature bearing on getting older bargains with frequent degenerative adjustments and paints a grim photograph for the getting older important fearful process when it comes to restoration of functionality following trauma.

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Extra resources for Aging and Recovery of Function in the Central Nervous System

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And Wallace, R. , 1976, Aging and the central nervous system, Exp. Aging Res. 2:125-164. Bourne, G. , 1973, Lipofuscin, Prog. Brain Res. 40:187-201. 40 C. ROBERT ALMLI Brobeck, J. , and Long, C. N. , 1943, Experimental hypothalamic hyperphagia in the albino rat, Yale J. BioI. Med. 15:831-853. , 1973, Aging of the vertebrate brain, in: Development and Aging in the Nervous System (M. ), Academic Press, New York, pp. 131-134. , 1964, Aging, the Biology of Senescence, Holt, Rinehart and Winston, New York.

Bioi. Med. 126:184-190. Poland, R. , Weichsel, M. , and Rubin, R. , 1981, Neonatal dexamethasone administration. 1. Temporary delay of development of the circadian serum corticosterone rhythm in rats, Endocrinology 108: 1049-1054. Prineas, J. , 1979, Multiple sclerosis: Presence of lymphatic capillaries and lymphoid tissue in brain and spinal cord, Science 203:1123-1125. , Ordy, J. , 1973, Age and sex differences in mortality after proton irradiation of the brain during maturity and aging in C57BLI IO mice, 1.

2. Aging-Related Changes in Behavioral and Physiological Function The aging process is associated with a wide variety of changes in metabolic, autonomic, and endocrine function, and many of the changes are detrimental to organismic adaptability and, therefore viability. For example, the aging process is typically associated with decreases in maximal breathing capacity, cardiac output, and a decreased ability of the individual to adapt to environmental stressors. , 1980). , 1963); and increased heart size.

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