2008-2009 Basic and Clinical Science Course: Section 9: by Ramana S. Moorthy, MD

By Ramana S. Moorthy, MD

A dialogue of the medical method of uveitis results in largely rewritten chapters on noninfectious (autoimmune) and infectious sorts of uveitis. additionally lined are endophthalmitis, masquerade syndromes, and issues of uveitis. A dialogue on ocular involvement in AIDS has been up-to-date. The part on immunology describes the human immune reaction in phrases that make it hugely available to readers.

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Extra resources for 2008-2009 Basic and Clinical Science Course: Section 9: Intraocular Inflammation and Uveitis (Basic and Clinical Science Course 2008-2009)

Sample text

Again, some of the toxin is taken up by the LCs, internalized over the next 4-18 hours into endocytic compartments, and processed in a way that can be recognized by T lymphocytes. If a memory T lymphocyte is present at the cutaneous site, then the processing and effector phases occur within 24 hours at the site, as the memory T lymphocyte becomes activated upon interacting with the LC. In addition, some LCs leave the skin, enter the draining node, and encounter memory T lymphocytes there. Processing during the secondary response is much quicker, and within 24 hours restimulated memory cells enter the circulation and migrate to the 29 30 .

To allow circulation of immunomodulatory factors in aqueous humor See Clinical Example 3-2. Foster CS. Streilein Jw. Basic immunology. In: Foster CS, Vitale AT, eds. Diagnosis and Treat- ment of Uveitis. Philadelphia: Saunders; 2002:34-78. Sugita S, Ng TF, Lucas PJ, Gress RE, Streilein Jw. B7+ iris pigment epithelium T regulatory cells; both suppress CTLA-4+ T cells. J Immunol. 2006;176:118Zamiri P, Masli S, Kitaichi N, Taylor AW, Streilein Jw. lhrombospondin immune privilege of the eye. Invest Ophthalmol CLINICAL induce CD8+ 127.

For example, in the neural response to the patellar deep tendon reflex, the afferent response begins with the recognition of a stimulus (the activation of the stretch receptor by percussion of the patellar tendon), followed by transformation of the stimulus into a neural signal that is conveyed along an afferent neuron into the central nervous system. In the central nervous system, complex neural processing occurs. Finally, along an efferent neuron, the neural signal is conveyed back to the site (quadriceps muscle), which is activated to contract (ie, an effector response).

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